Five-Year Survival 60 to 70 percent Stage III Standard Treatment • Maxillary sinus: Surgery with high-dose pre- or postoperative radiotherapy . • Ethimoid sinus: Extensive surgery followed by radiotherapy. • Sphenoid sinus: Radiotherapy. • Nasal cavity: Surgery or radiotherapy alone. Usually postoperative radiotherapy is preferred. • Inverting papilloma: Same as Stage II. Radiotherapy may be needed if further surgery is unsuccessful. • Melanomas and sarcomas: Surgery if possible, otherwise radiotherapy. • Midline granuloma: Radiotherapy. • Nasal vestibule: Radiation first and surgery later if needed. Clinical trials are in progress for ethmoid sinus and nasal cavity tumors, using chemotherapy combinations in addition to surgery or radiotherapy. Five-Year Survival 25 to 35 percent